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Autoimmunity: Basophils in autoimmune and inflammatory diseases
M. Sharma,
Published in Nature Publishing Group
2015
PMID: 25422004
Volume: 11
   
Issue: 3
Pages: 129 - 131
Abstract
Basophils are classically known for their pathogenic role in asthma and allergic skin conditions. However, reports suggest that basophil activation mediated by autoreactive IgE, thymic stromal lymphopoietin or Toll-like receptors has an important role in the pathogenesis of lupus nephritis, eosinophilic oesophagitis and IgG4-related diseases, respectively.
About the journal
JournalNature Reviews Rheumatology
PublisherNature Publishing Group
ISSN17594790
Open AccessNo