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Copper(I)-Catalyzed Decarboxylative N-Phosphorylation: Modular Preparation of N-Acyl Iminophosphoranes Using Dioxazolones and Phosphines
Jinhwan Park, Anattil Krishnapriya Unnikrishnan, Yeongmi Park, Minsuk Kim, Tyler Reidl W., , Jongwoo Son
Published in John Wiley and Sons Inc
2023
Volume: 365
   
Issue: 24
Abstract
Dioxazolones and phosphines have been used to access N-acyl iminophosphoranes in copper(I) catalysis under simple thermal conditions. The synthetic utility of this protocol is demonstrated by a broad range of substrates with an excellent atom-economy. The optimization process showed that copper demonstrated as catalytic amount toward the targeted transformation. Functionalization studies of N-acyl iminophosphoranes were also conducted. Our reaction protocol is compatible with an example of a bioactive motif-containing N-acyl iminophosphorane analogue. © 2023 Wiley-VCH GmbH.
About the journal
JournalAdvanced Synthesis and Catalysis
PublisherJohn Wiley and Sons Inc
ISSN16154150