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Erythrocyte Sedimentation: Collapse of a High-Volume-Fraction Soft-Particle Gel
A. Darras, , T. John, G. Gompper, L. Kaestner, D.A. Fedosov, C. Wagner
Published in American Physical Society
PMID: 35275655
Volume: 128
Issue: 8
The erythrocyte sedimentation rate is one of the oldest medical diagnostic methods whose physical mechanisms remain debatable today. Using both light microscopy and mesoscale cell-level simulations, we show that erythrocytes form a soft-particle gel. Furthermore, the high volume fraction of erythrocytes, their deformability, and weak attraction lead to unusual properties of this gel. A theoretical model for the gravitational collapse is developed, whose predictions are in agreement with detailed macroscopic measurements of the interface velocity. © 2022 American Physical Society.
About the journal
JournalPhysical Review Letters
PublisherAmerican Physical Society