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Multimerized IgG1 Fc molecule as an anti-inflammatory agent
E. Stephen-Victor,
Published in Nature Publishing Group
2018
PMID: 29760434
Volume: 14
   
Issue: 7
Pages: 390 - 392
Abstract
The success of intravenous immunoglobulin immunotherapy in autoimmune diseases has inspired the development of novel Fc-based therapeutics, in particular, multimerized polyvalent Fc molecules. A new study reports that a recombinant IgG1 Fc hexamer alleviates acute and chronic autoimmune diseases in mice. © 2018 Macmillan Publishers Ltd., part of Springer Nature.
About the journal
JournalNature Reviews Rheumatology
PublisherNature Publishing Group
ISSN17594790
Open AccessNo