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Nb4C3Tx (MXene)/Au/DNA Aptasensor for the Ultraselective Electrochemical Detection of Lead in Water Samples

, Ravi P. Pandey, Khadeeja A Jabbar, Khaled A Mahmoud
Published in John Wiley & Sons, Inc.
2022
Volume: 34
   
Issue: 10
Abstract

An electrochemical apt sensor was designed for the ultras elective and sensitive detection of Pb2+ by using lead-specific binding DNA oligonucleotide as the molecular recognition element on Au nanoparticles/Nb4C3Tx MXene (Au@Nb4C3Tx) modified electrode. The Au@Nb4C3Tx is conjugated with thiol-modified lead-binding DNA through the Au−S bond. The DNA−Au@Nb4C3Tx modified glassy carbon electrode exhibited ultrahigh selectivity and enhanced response towards the detection of Pb2+ with a detection limit of 4 nM and linear range of 10 nM to 5 μM. This work has proved the possibility of using Nb4C3Tx as a robust immobilization platform for DNA oligonucleotides towards different environmental sensing and biomedical applications.

About the journal
JournalData powered by TypesetAn International Journal Devoted to Electroanalysis, Sensors & Bioelectronic Devices
PublisherData powered by TypesetJohn Wiley & Sons, Inc.
ISSN10400397
Open AccessNo