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Solvent free synthesis of 3,4-dihydropyrimidine-2-(1H)-ones/thiones catalyzed by N,O-bis(trimethylsilyl)acetamide and dicyclohexyl carbodimide
Y. Murthy L. N., Abdul Rajack,
Published in ELSEVIER SCIENCE BV
2016
Volume: 9
   
Issue: 2
Pages: S1740 - S1746
Abstract
We report herein, the usage of N,O-bis(trimethylsilyl) acetamide (BSA) and dicyclohexyl carbodimide (DCC) as two new catalysts for three component condensation of an aldehyde, ethyl acetoacetate and urea/thiourea under solvent free conditions at 100 degrees C to afford the corresponding 3,4-dihydropyrimidine-2-(1H)-ones/thiones (DHPMs) in good to excellent yields. A comparative study of these two catalysts was made and presented. (C) 2012 Production and hosting by Elsevier B.V. on behalf of King Saud University.
About the journal
JournalARABIAN JOURNAL OF CHEMISTRY
PublisherELSEVIER SCIENCE BV
ISSN1878-5352